Programプログラム
Keynote Lectures 1
December 13 (Sat) 13:00-14:00
| Chair | Issei Komuro | International University of Health and Welfare/ University of Tokyo |
|---|---|---|
| Speaker | Applications of AI in Cardiovascular Development and Disease Modeling | |
| Sean M Wu |  Professor of Medicine and Pediatrics Department of Medicine and Cardiovascular Institute Stanford University School of Medicine, USA |
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Keynote Lecture 2
December 14 (Sun) 9:00-10:00
| Chair | Yasuchika Takeishi | Fukushima Medical University Hospital |
|---|---|---|
| Speaker | Understanding Human Cardiac Metabolism | |
| Zoltan Pierre Arany |  Samuel Bellet Professor of Cardiology Cardiovascular Institute and Institute Diabetes Obesity and Metabolism Department of Medicine, Perelman School of Medicine University of Pennsylvania, USA |
|
Symposium 1Nucleic Acid Therapeutics, Genome Editing, and Omics Technologies
December 13 (Sat) 9:00-10:30
| Chair | Koh Ono | Kyoto University |
|---|---|---|
| Seitaro Nomura | The University of Tokyo | |
| Speaker | Acid-Degradable PEG-Lipid Nanoparticles Enable Efficient Cardiac mRNA Delivery in Vivo | |
| Tomohiro Nishino | Kyoto University Graduate School of Medicine | |
| Development of Synthetic Nucleic Acids Targeting MicroRNAs for Therapeutic Applications | ||
| Takahiro Horie | Kyoto University Graduate School of Medicine | |
| Therapeutic Genome Editing of RBM20-Associated Dilated Cardiomyopathy | ||
| Takahiko Nishiyama | Keio University School of Medicine | |
| Engineering Compact Cas Proteins for Cardiovascular Diseases | ||
| Atsushi Hoshino | Kyoto Prefectural University of Medicine | |
| Development of Gene-Therapy for End-Stage Heart Failure and Ischemic Cardiomyopathy | ||
| Toshiyuki Ko | The University of Tokyo | |
Symposium 2Regenerative Medicine and Development
December 13 (Sat) 14:10-15:40
| Chair | Masaki Ieda | Keio University |
|---|---|---|
| Hideki Uosaki | Jichi Medical University | |
| Speaker | Production of Cardiac Microtissues from Human iPSCs for Regenerative Therapy and Disease Modeling | |
| Shugo Tohyama | Fujita Medical Innovation Center Tokyo / Kanagawa Institute of Industrial Science and Technology | |
| Heart Failure Treatment through Cardiac Regeneration and Antifibrosis | ||
| Taketaro Sadahiro | Keio University School of Medicine | |
| Cardiac gene therapy for dilated cardiomyopathy caused by bi-allelic loss-of-function mutations in BAG5 | ||
| Hidetaka Kioka | The University of Osaka Graduate School of Medicine | |
| Maturation of Cardiac Organoids And Their Promise for Future Cardiovascular Therapies | ||
| Kozue Murata | Kyoto University | |
| Taurine Stabilizes Mitochondrial tRNALys and Restores Bioenergetics in KARS1 Related Cardiomyopathy | ||
| Takeshi Tokuyama | Jichi Medical University | |
Symposium 3Mitochondria, Metabolism and Cardiovascular diseases
December 14 (Sun) 10:10-11:40
| Chair | Naotada Ishihara | Osaka University |
|---|---|---|
| Norihiko Takeda | The University of Tokyo | |
| Speaker | Reverse genetic studies on mutant mitochondrial DNAs in mice: Insights for understanding mitochondrial DNA-based disorders | |
| Kazuto Nakada | University of Tsukuba | |
| Lipid metabolism through mitochondria | ||
| Yasushi Tamura | Yamagata University | |
| Essential role of coordinated dynamics of the mitochondrial membranes and nucleoids in cardiac function | ||
| Takaya Ishihara | Shimane University | |
| Novel Regulatory Mechanism of Myocardial Inflammation Mediated by Mitochondrial DNA | ||
| Shouji Matsushima | Kyushu University | |
| Linking Inflammation to Metabolic Changes in Heart Disease | ||
| Yasutomi Higashikuni | Jichi Medical University | |
Symposium 4Senescence and Cardiovascular aging
December 14 (Sun) 15:30-17:00
| Chair | Eiji Hara | Osaka University |
|---|---|---|
| Yuichi Oike | Kumamoto University | |
| Speaker | Capillary deterioration due to aging and its regulation | |
| Nobuyuki Takakura | The University of Osaka | |
| Age-related loss of organ-specific endothelial cell heterogeneity and its impact on organismal aging | ||
| Shigetomo Fukuhara | Nippon Medical School | |
| Innate immune memory in age-associated diseases | ||
| Ichiro Manabe | Chiba University Graduate School of Medicine | |
| Exploring the Molecular Basis of Cardiac Aging | ||
| Michio Sato | Kumamoto University | |
| Roles and Mechanisms of Cellular Senescence in Aging and Aging-Associated Diseases: Insights into Microbial Interactions | ||
| Eiji Hara | Osaka University | |
Award Session
December 13 (Sat) 10:40-11:40
| Chair | Ichiro Manabe | Chiba University Graduate School of Medicine |
|---|---|---|
| Motoaki Sano | Yamaguchi University School of Medicine | |
| Speaker | TGM2-Mediated Histone Serotonylation Represents a Novel Epigenetic Cardioprotective Mechanism in HFpEF | |
| Ryo Ogawara | Fukushima Medical University | |
| SVEP1: a novel fibroblast-derived blood biomarker for cardiac fibrosis | ||
| Naoya Kuwahara | Kobe University Graduate School of Medicine | |
| Sipa1 Drives a Maladaptive Fibroblast-Myeloid Axis after Myocardial Infarction | ||
| Seien Ko | Keio University School of Medicine | |
| SAAM-1 Immunization Mitigates Cardiac Remodeling and Vascular Lesions in Murine Models of Cardiovascular Disease | ||
| ChiehLun Hsiao | Juntendo University Graduate School of Medicine | |
| Tet2-Mutant Clonal Hematopoiesis Drives Aortic Aneurysm Progression via Macrophage-to-Osteoclast-like Differentiation | ||
| Jun Yonekawa | Nagoya University School of Medicine | |
Progress Report for Basic Research
December 13 (Sat) 15:50-17:20
| Chair | Mari Ishida | Hiroshima Shudo University |
|---|---|---|
| Ichiro Shiojima | National Cerebral and Cardiovascular Center | |
| Speaker | Epicardial Fat-Mediated Lymphatic Impairment Contributes to Atrial Fibrillation Development | |
| Ichitaro Abe | The University of Tokyo | |
| Development of a novel antiarrhythmic therapy using antisense oligonucleotide to improve the prognosis of cardiomyopathy | ||
| Hideaki Inazumi | The University of Tokyo | |
| Multi-omics analysis on atrial structural remodeling in patients with atrial fibrillation | ||
| Kosuke Sawami | The University of Tokyo | |
| Characterization of Cardiac FAPs and Therapeutic Strategies via Primary Cilia | ||
| Daishi Yamakawa | Mie University | |
| Role of interleukin 34 in pulmonary hypertension due to pulmonary fibrosis | ||
| Tetsuro Yokokawa | Fukushima Medical University | |
Grant Session in Basic Research
December 14 (Sun) 13:00-14:00
| Chair | Shinsuke Yuasa | Okayama University |
|---|---|---|
| Soichi Sano | National Cerebral and Cardiovascular Center | |
| Speaker | The Development of Novel Therapeutics Targeting Gut Dysbiosis in Pulmonary Arterial Hypertension | |
| Ryotaro Asano | National Cerebral and Cardiovascular Center | |
| Understanding the Pathological Mechanism of the Cardio-Sarcopenia Syndrome Caused by Age-related Change in Macrophages | ||
| Mao Kuriki | Institute of Science Tokyo | |
| Metabolic Reprogramming of Vascular Endothelial Stem Cells as a Novel Therapeutic Target in HFpEF Pathogenesis | ||
| Yuki Tatekoshi | Sapporo Medical University | |
| Elucidation of New Pathophysiology of Heart Failure and Drug Discovery Applications Focusing on Heart-Kidney Interaction using Organoid Technology | ||
| Hidenori Tani | Fujita Health University | |
| Lineage-Specific Tissue Macrophage Mediated Pathological Microenvironments in Cardiac Fibrosis | ||
| Norika Liu | Kumamoto University | |
JCS/U45 ISHR Joint SymposiumRising star session
December 14 (Sun) 14:10-15:20
| Chair | Atsuko Okazaki | Juntendo University |
|---|---|---|
| Yoshimitsu Yura | Nagoya University Hospital | |
| Speaker | Vascular Homeostasis as a Foundation for Cancer Immune Activation | |
| Megumu Tanaka | Shinshu University | |
| RNA regulation as a protective mechanism in cardiac stress and remodeling | ||
| Teruki Sato | Akita university | |
| A Novel BAT-derived Pro-Fibrotic Protein Promotes Pathogenesis in Cardiovascular-metabolic Diseases | ||
| Yung Ting Hsiao | National Cardiovascular Center Research Institute | |
| Spatial Omics Analysis of Immune Cell Infiltration in Cardiac Sarcoidosis | ||
| Mikako Katagiri | The University of Tokyo | |
| Elucidation of the protective effect of endocardial-derived tissue macrophages against myocardial fibrosis | ||
| Norika Liu | Kumamoto University | |
| Heart failure-specific cardiac fibroblasts promote cardiac dysfunction via the MYC-CXCL1-CXCR2 signaling axis | ||
| Jin Komuro | The University of Tokyo / Keio University | |
Poster Session
December 13 (Sat) 17:30-19:00
Poster Program Click here to download
* Beverages and snacks will be served during the session.
Sponsored Seminars
| Luncheon Seminar1 | December 13 (Sat) 12:00-12:50 | by Nippon Boehringer Ingelheim Co., Ltd. |
|---|---|---|
| Morning Seminar | December 14 (Sun) 8:15-8:50 | by Daiichi Sankyo Co., Ltd |
| Luncheon Seminar2 | December 14 (Sun) 12:00-12:50 | by Novartis Pharma K.K / Otsuka Pharmaceutical Co., Ltd. |
